FAQ

No. No venom, no toxin, no animal-derived material. SYN-AKE® is a fully synthetic peptide modeled on one short sequence from a venom peptide. Nothing else from the venom was used or recreated.

No. This is a topical cosmetic serum applied to the surface of your skin, not a medical procedure.

Your expressions don’t change. Nothing is paralyzed. No plastic face. What changes, is how deep a crease your expressions leave behind.

Ten ingredients, no fragrance, no essential oils, no dye. That’s a short list of things to react to, which is one of the advantages of a minimal formula.

Occasional mild, transient tingling has been reported with SYN-AKE® formulas. If you’re reactive or allergy-prone, patch test on a small area first.

Apply to the outer eye area and crow’s feet. Avoid direct contact with the eye itself. If it gets in your eye, rinse thoroughly.

Yes. REFINE can be used alongside retinol, vitamin C, moisturizer and other common skincare products.

Apply REFINE to clean, dry skin, let it absorb, then continue with the rest of your routine.

Yes. Expression lines deepen through repeated creasing. SYN-AKE® helps reduce the repeated pull behind that crease, so consistent use can help soften the lines you have while reducing the repeated creasing that can make them deeper over time.

Improve the line you see today. Help keep it from becoming a deeper crease tomorrow.

You don’t have to wait 90 days to start seeing a difference.

The hydration side of REFINE begins working from the first applications, helping skin look fuller, smoother and less dry.

SYN-AKE® research begins showing early visible expression-line changes around Days 7–14, with Day 28 as the primary expression-line checkpoint.

From there, continued hydration and niacinamide give the skin around those lines more time to improve through Days 60 and 90.

Day 28 is the checkpoint. Give it 90 to see how far you can take it.

Yes, continued use matters if you want to maintain the SYN-AKE® expression-line effect.

The effect is reversible, so consistent use matters. Continued use also gives the hydration and skin-support side of the formula more time to keep working.

Think maintenance with momentum.

Yes. The mechanism has nothing to do with gender. Men often have deeper forehead lines and stronger 11s, partly from thicker skin and partly from decades of less sun protection, and those are the two zones this was built for.

One bottle is 15 mL / 0.5 fl oz, approximately a 30-day supply when REFINE is used as directed, morning and night.

That’s why the 1-, 2- and 3-bottle options correspond to approximately 30, 60 and 90 days of use.

Room temperature, out of direct sunlight. No refrigeration needed. Six months once opened, as indicated on the carton.

2 to 3 business days within the US. Ships from Texas.

A synthetic peptide developed by Pentapharm in Switzerland and now produced by DSM. It’s modeled on one sequence from Waglerin-1, a peptide found in temple viper venom. INCI name: Dipeptide Diaminobutyroyl Benzylamide Diacetate.

Assembled in the USA. Cruelty free. No animal testing.

Yes. Regenyx Refine is a vegan formula.

We work Monday through Friday, 9 to 5 Central Time, and you can reach us at support@regenyx.life.